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T. J. Clark Liquid Vitamin B1
(Thiamine):
Thiamine, or vitamin B1, a colorless, crystalline substance, acts as a catalyst in carbohydrate metabolism, enabling pyruvic acid to be absorbed and carbohydrates to release their energy, and is needed for normal muscle tone of vital internal organs. Thiamin increases circulation and assist in the production of hydrochloric acid, blood formation and carbohydrate metabolism. Thiamine also plays a role in the synthesis of nerve-regulating substances. The first recognized vitamin deficiency disease was beriberi, a condition that is manifested by numerous neurological and metabolic disorders. Sufficient thiamine in the diet is a sure cure for beriberi, a fact that was established over a long period of time through crude dietary experiments by the Chinese, Japanese, and Dutch. Biochemically, thiamine forms a coenzyme after phosphorylation by an ATP-dependent pyrophosphorylase. Thiamine pyrophosphate contains a substituted pyrimidine nitrogen heterocyclic ring and a thiazole nitrogen-sulfur heterocycle. The thiazole moiety is responsible for the coenzyme's activity in pyruvate metabolism where it acts to perform a nonoxidative decarboxylation. Clinically, thiamine helps to maintain normal function of the nervous system, muscles, and heart, and is necessary for normal growth and development. Common sources of thiamine are kidney, liver, brewer's yeast, flour, beans, pork, salmon, soybeans, and wheat germ. Symptoms of thiamine deficiency are:
Severe deficiency leads to beriberi, pain in the
arms and legs, heart enlargement and fluid accumulation.
DEFICIENCY SYMPTOMS:
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